Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging

Defects in mitochondrial biogenesis and function are common in many neurodegenerative disorders, including Huntington’s disease (HD). We have previously shown that in yeast models of HD, enhancement of mitochondrial biogenesis through overexpression of Hap4, the catalytic subunit of the transcriptio...

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Detalles Bibliográficos
Autores principales: Ruetenik, Andrea L., Ocampo, Alejandro, Ruan, Kai, Zhu, Yi, Li, Chong, Zhai, R. Grace, Barrientos, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349013/
https://www.ncbi.nlm.nih.gov/pubmed/28357370
http://dx.doi.org/10.15698/mic2016.08.518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349013/
https://www.ncbi.nlm.nih.gov/pubmed/28357370
http://dx.doi.org/10.15698/mic2016.08.518

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