A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid β Toxicity in the Drosophila Brain

The accumulation of amyloid β peptide (Aβ) in the brain of Alzheimer’s disease (AD) patients begins many years before clinical onset. Such process has been proposed to be pathogenic through the toxicity of Aβ soluble oligomers leading to synaptic dysfunction, phospho-tau aggregation and neuronal los...

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Detalles Bibliográficos
Autores principales: Belfiori-Carrasco, Lautaro F., Marcora, María S., Bocai, Nadia I., Ceriani, M. Fernanda, Morelli, Laura, Castaño, Eduardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349081/
https://www.ncbi.nlm.nih.gov/pubmed/28352227
http://dx.doi.org/10.3389/fnagi.2017.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349081/
https://www.ncbi.nlm.nih.gov/pubmed/28352227
http://dx.doi.org/10.3389/fnagi.2017.00061

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