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The role of transcriptional ‘futile cycles’ in autophagy and microbial pathogenesis

Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating preformed autophagy-related (Atg) proteins to repress autopha...

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Detalles Bibliográficos
Autores principales: Hu, Guowu, McQuiston, Travis, Bernard, Amélie, Park, Yoon-Dong, Qiu, Jin, Vural, Ali, Zhang, Nannan, Waterman, Scott R., Blewett, Nathan H., Myers, Timothy G., Kehrl, John H., Uzel, Gulbu, Klionsky, Daniel J., Williamson, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349103/
https://www.ncbi.nlm.nih.gov/pubmed/28357306
http://dx.doi.org/10.15698/mic2015.08.221