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Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy

Aldo–keto reductases comprise of AKR1C1–AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. Recent studies have provided evidences of strong correlation between the expression levels of these family memb...

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Detalles Bibliográficos
Autores principales: Zeng, Chen-Ming, Chang, Lin-Lin, Ying, Mei-Dan, Cao, Ji, He, Qiao-Jun, Zhu, Hong, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349110/
https://www.ncbi.nlm.nih.gov/pubmed/28352233
http://dx.doi.org/10.3389/fphar.2017.00119