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Balanced CoQ(6) biosynthesis is required for lifespan and mitophagy in yeast

Coenzyme Q is an essential lipid with redox capacity that is present in all organisms. In yeast its biosynthesis depends on a multiprotein complex in which Coq7 protein has both catalytic and regulatory functions. Coq7 modulates CoQ(6) levels through a phosphorylation cycle, where dephosphorylation...

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Detalles Bibliográficos
Autores principales: González-Mariscal, Isabel, Martín-Montalvo, Aléjandro, Ojeda-González, Cristina, Rodríguez-Eguren, Adolfo, Gutiérrez-Ríos, Purificación, Navas, Plácido, Santos-Ocaña, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349121/
https://www.ncbi.nlm.nih.gov/pubmed/28357388
http://dx.doi.org/10.15698/mic2017.02.556