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Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress

Fructose-1,6-bisphosphatase (FBP1) is a key enzyme in the evolutionary conserved pathway of gluconeogenesis. We had shown in an earlier study that FBP1 is involved in the response and sensitivity to methyl-methanesulfonate (MMS)-induced DNA damage in yeast. In the work presented here we performed an...

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Detalles Bibliográficos
Autores principales: Ghanem, Ali, Kitanovic, Ana, Holzwarth, Jinda, Wölfl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349122/
https://www.ncbi.nlm.nih.gov/pubmed/28357389
http://dx.doi.org/10.15698/mic2017.02.557