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Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress, we investigate its role upon the production o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349127/ https://www.ncbi.nlm.nih.gov/pubmed/28357216 http://dx.doi.org/10.15698/mic2014.11.173 |