Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion

Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress, we investigate its role upon the production o...

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Detalles Bibliográficos
Autores principales: Delic, Marizela, Graf, Alexandra B., Koellensperger, Gunda, Haberhauer-Troyer, Christina, Hann, Stephan, Mattanovich, Diethard, Gasser, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349127/
https://www.ncbi.nlm.nih.gov/pubmed/28357216
http://dx.doi.org/10.15698/mic2014.11.173

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