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Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells

The target of rapamycin (TOR) is an important signaling pathway on a hierarchical network of interacting pathways regulating central biological processes, such as cell growth, stress response and aging. Several lines of evidence suggest a functional link between TOR signaling and sphingolipid metabo...

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Detalles Bibliográficos
Autores principales: Teixeira, Vitor, Medeiros, Tânia C., Vilaça, Rita, Moradas-Ferreira, Pedro, Costa, Vítor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349163/
https://www.ncbi.nlm.nih.gov/pubmed/28357207
http://dx.doi.org/10.15698/mic2014.01.121