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Transcriptional and genomic mayhem due to aging-induced nucleosome loss in budding yeast

All eukaryotic genomes are assembled into a nucleoprotein structure termed chromatin, which is comprised of regular arrays of nucleosomes. Each nucleosome consists of eight core histone protein molecules around which the DNA is wrapped 1.75 times. The ultimate consequence of packaging the genome int...

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Detalles Bibliográficos
Autores principales: Hu, Zheng, Chen, Kaifu, Li, Wei, Tyler, Jessica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349203/
https://www.ncbi.nlm.nih.gov/pubmed/28357234
http://dx.doi.org/10.15698/mic2014.04.139