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Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning

Current pharmacological treatments for major depressive disorder (MDD) are ineffective in a significant proportion of patients, and the identification of new antidepressant compounds has been difficult. ‘Connectivity mapping’ is a method that can be used to identify drugs that elicit similar downstr...

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Detalles Bibliográficos
Autores principales: Powell, Timothy R, Murphy, Tytus, Lee, Sang H, Price, Jack, Thuret, Sandrine, Breen, Gerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349314/
https://www.ncbi.nlm.nih.gov/pubmed/28208023
http://dx.doi.org/10.1177/0269881117691467