Cargando…
Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning
Current pharmacological treatments for major depressive disorder (MDD) are ineffective in a significant proportion of patients, and the identification of new antidepressant compounds has been difficult. ‘Connectivity mapping’ is a method that can be used to identify drugs that elicit similar downstr...
Autores principales: | Powell, Timothy R, Murphy, Tytus, Lee, Sang H, Price, Jack, Thuret, Sandrine, Breen, Gerome |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349314/ https://www.ncbi.nlm.nih.gov/pubmed/28208023 http://dx.doi.org/10.1177/0269881117691467 |
Ejemplares similares
-
Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood
por: Powell, Timothy R., et al.
Publicado: (2017) -
The genome‐wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response
por: Powell, Timothy R., et al.
Publicado: (2017) -
Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells
por: de Lucia, Chiara, et al.
Publicado: (2021) -
Predicting progression to Alzheimer’s disease with human hippocampal progenitors exposed to serum
por: Maruszak, Aleksandra, et al.
Publicado: (2023) -
Effects of Diet on Brain Plasticity in Animal and Human Studies: Mind the Gap
por: Murphy, Tytus, et al.
Publicado: (2014)