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Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array
The balance between acetylation and deacetylation of histone proteins plays a critical role in the regulation of genomic functions. Aberrations in global levels of histone modifications are linked to carcinogenesis and are currently the focus of intense scrutiny and translational research investment...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349387/ https://www.ncbi.nlm.nih.gov/pubmed/28326191 http://dx.doi.org/10.1038/cddiscovery.2016.77 |