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The use of small-molecule structures to complement protein–ligand crystal structures in drug discovery
Many ligand-discovery stories tell of the use of structures of protein–ligand complexes, but the contribution of structural chemistry is such a core part of finding and improving ligands that it is often overlooked. More than 800 000 crystal structures are available to the community through the Camb...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349436/ https://www.ncbi.nlm.nih.gov/pubmed/28291759 http://dx.doi.org/10.1107/S2059798317000675 |