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Gab3 overexpression in human glioma mediates Akt activation and tumor cell proliferation

This current study tested expression and potential biological functions of Gab3 in human glioma. Gab3 mRNA and protein expression was significantly elevated in human glioma tissues and glioma cells. Its level was however low in normal brain tissues and primary human astrocytes. In both established (...

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Detalles Bibliográficos
Autores principales: Jia, Pifeng, Li, Feng, Gu, Weiting, Zhang, Weifeng, Cai, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349442/
https://www.ncbi.nlm.nih.gov/pubmed/28291820
http://dx.doi.org/10.1371/journal.pone.0173473