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Gab3 overexpression in human glioma mediates Akt activation and tumor cell proliferation
This current study tested expression and potential biological functions of Gab3 in human glioma. Gab3 mRNA and protein expression was significantly elevated in human glioma tissues and glioma cells. Its level was however low in normal brain tissues and primary human astrocytes. In both established (...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349442/ https://www.ncbi.nlm.nih.gov/pubmed/28291820 http://dx.doi.org/10.1371/journal.pone.0173473 |