Phosphoproteomics Reveals HMGA1, a CK2 Substrate, as a Drug-Resistant Target in Non-Small Cell Lung Cancer

Although EGFR tyrosine kinase inhibitors (TKIs) have demonstrated good efficacy in non-small-cell lung cancer (NSCLC) patients harboring EGFR mutations, most patients develop intrinsic and acquired resistance. We quantitatively profiled the phosphoproteome and proteome of drug-sensitive and drug-res...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Pan, Szu-Hua, Tsai, Chia-Feng, Kuo, Ting-Chun, Hsu, Yuan-Ling, Yen, Hsin-Yung, Choong, Wai-Kok, Wu, Hsin-Yi, Liao, Yen-Chen, Hong, Tse-Ming, Sung, Ting-Yi, Yang, Pan-Chyr, Chen, Yu-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349541/
https://www.ncbi.nlm.nih.gov/pubmed/28290473
http://dx.doi.org/10.1038/srep44021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349541/
https://www.ncbi.nlm.nih.gov/pubmed/28290473
http://dx.doi.org/10.1038/srep44021

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