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TLR-exosomes exhibit distinct kinetics and effector function

The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular exosomes play a role in immunity, but to date their exact contribution to the dissemination of the TLR response is unknown. Here we show that e...

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Detalles Bibliográficos
Autores principales: Srinivasan, Swetha, Su, Michelle, Ravishankar, Shashidhar, Moore, James, Head, PamelaSara, Dixon, J. Brandon, Vannberg, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349571/
https://www.ncbi.nlm.nih.gov/pubmed/28290538
http://dx.doi.org/10.1038/srep41623