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Extracellular matrix and α(5)β(1) integrin signaling control the maintenance of bone formation capacity by human adipose-derived stromal cells
Stromal vascular fraction (SVF) cells of human adipose tissue have the capacity to generate osteogenic grafts with intrinsic vasculogenic properties. However, adipose-derived stromal/stem cells (ASC), even after minimal monolayer expansion, display poor osteogenic capacity in vivo. We investigated w...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349595/ https://www.ncbi.nlm.nih.gov/pubmed/28290502 http://dx.doi.org/10.1038/srep44398 |