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Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease

Neuroimaging genetics is an emerging field that aims to identify the associations between genetic variants (e.g., single nucleotide polymorphisms (SNPs)) and quantitative traits (QTs) such as brain imaging phenotypes. In recent studies, in order to detect complex multi-SNP-multi-QT associations, bi-...

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Detalles Bibliográficos
Autores principales: Hao, Xiaoke, Li, Chanxiu, Du, Lei, Yao, Xiaohui, Yan, Jingwen, Risacher, Shannon L., Saykin, Andrew J., Shen, Li, Zhang, Daoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349597/
https://www.ncbi.nlm.nih.gov/pubmed/28291242
http://dx.doi.org/10.1038/srep44272