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Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling

Adaptive thermogenesis and cold-induced activation of uncoupling protein 1 (Ucp1) in brown adipose tissue in rodents is well-described and attributed to sympathetic activation of β-adrenergic signaling. The arrestin domain containing protein Arrdc3 is a regulator of obesity in mice and also appears...

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Detalles Bibliográficos
Autores principales: Carroll, Shannon H., Zhang, Ellen, Wang, Bing F., LeClair, Katherine B., Rahman, Arifeen, Cohen, David E., Plutzky, Jorge, Patwari, Parth, Lee, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349670/
https://www.ncbi.nlm.nih.gov/pubmed/28291835
http://dx.doi.org/10.1371/journal.pone.0173823