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Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling
Adaptive thermogenesis and cold-induced activation of uncoupling protein 1 (Ucp1) in brown adipose tissue in rodents is well-described and attributed to sympathetic activation of β-adrenergic signaling. The arrestin domain containing protein Arrdc3 is a regulator of obesity in mice and also appears...
Autores principales: | Carroll, Shannon H., Zhang, Ellen, Wang, Bing F., LeClair, Katherine B., Rahman, Arifeen, Cohen, David E., Plutzky, Jorge, Patwari, Parth, Lee, Richard T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349670/ https://www.ncbi.nlm.nih.gov/pubmed/28291835 http://dx.doi.org/10.1371/journal.pone.0173823 |
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