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Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitization

We studied a role of the inducible heat shock protein 70 (Hsp70) in cellular response to radiosensitizing treatments with inhibitors of the heat shock protein 90 (Hsp90) chaperone activity. Cell lines derived from solid tumors of different origin were treated with the Hsp90 inhibitors (17AAG, geldan...

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Detalles Bibliográficos
Autores principales: Kudryavtsev, Vladimir A., Khokhlova, Anna V., Mosina, Vera A., Selivanova, Elena I., Kabakov, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349677/
https://www.ncbi.nlm.nih.gov/pubmed/28291803
http://dx.doi.org/10.1371/journal.pone.0173640