Cargando…
Microstructural white matter alterations in preclinical Alzheimer’s disease detected using free water elimination diffusion tensor imaging
Brain changes associated with Alzheimer’s disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD, neuronal loss and synaptic pathology are closely related to the cognitive dysfunction. Brain imaging methods that are tuned...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349685/ https://www.ncbi.nlm.nih.gov/pubmed/28291839 http://dx.doi.org/10.1371/journal.pone.0173982 |