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Microstructural white matter alterations in preclinical Alzheimer’s disease detected using free water elimination diffusion tensor imaging

Brain changes associated with Alzheimer’s disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD, neuronal loss and synaptic pathology are closely related to the cognitive dysfunction. Brain imaging methods that are tuned...

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Detalles Bibliográficos
Autores principales:	Hoy, Andrew R., Ly, Martina, Carlsson, Cynthia M., Okonkwo, Ozioma C., Zetterberg, Henrik, Blennow, Kaj, Sager, Mark A., Asthana, Sanjay, Johnson, Sterling C., Alexander, Andrew L., Bendlin, Barbara B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349685/ https://www.ncbi.nlm.nih.gov/pubmed/28291839 http://dx.doi.org/10.1371/journal.pone.0173982

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