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Autophagy regulates UBC9 levels during viral-mediated tumorigenesis

UBC9, the sole E2-conjugating enzyme required for SUMOylation, is a key regulator of essential cellular functions and, as such, is frequently altered in cancers. Along these lines, we recently reported that its expression gradually increases during early stages of human papillomavirus (HPV)-mediated...

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Detalles Bibliográficos
Autores principales: Mattoscio, Domenico, Casadio, Chiara, Miccolo, Claudia, Maffini, Fausto, Raimondi, Andrea, Tacchetti, Carlo, Gheit, Tarik, Tagliabue, Marta, Galimberti, Viviana E., De Lorenzi, Francesca, Pawlita, Michael, Chiesa, Fausto, Ansarin, Mohssen, Tommasino, Massimo, Chiocca, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349695/
https://www.ncbi.nlm.nih.gov/pubmed/28253371
http://dx.doi.org/10.1371/journal.ppat.1006262