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Retromer-driven membrane tubulation separates endosomal recycling from Rab7/Ypt7-dependent fusion

Endosomes are the major protein-sorting hubs of the endocytic pathway. They sort proteins destined for degradation into internal vesicles while in parallel recycling receptors via tubular carriers back to the Golgi. Tubule formation depends on the Rab7/Ypt7-interacting retromer complex, consisting o...

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Detalles Bibliográficos
Autores principales: Purushothaman, Latha Kallur, Arlt, Henning, Kuhlee, Anne, Raunser, Stefan, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349785/
https://www.ncbi.nlm.nih.gov/pubmed/28100638
http://dx.doi.org/10.1091/mbc.E16-08-0582