Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation

Insulin-like growth factor (IGF) signaling plays an important role in cell growth and proliferation and is implicated in regulation of cancer, metabolism, and aging. Here we report that IGF-1 level in blood and IGF-1 signaling demonstrates circadian rhythms. Circadian control occurs through cryptoch...

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Detalles Bibliográficos
Autores principales: Chaudhari, Amol, Gupta, Richa, Patel, Sonal, Velingkaar, Nikkhil, Kondratov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349790/
https://www.ncbi.nlm.nih.gov/pubmed/28100634
http://dx.doi.org/10.1091/mbc.E16-08-0624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349790/
https://www.ncbi.nlm.nih.gov/pubmed/28100634
http://dx.doi.org/10.1091/mbc.E16-08-0624

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