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Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation
Insulin-like growth factor (IGF) signaling plays an important role in cell growth and proliferation and is implicated in regulation of cancer, metabolism, and aging. Here we report that IGF-1 level in blood and IGF-1 signaling demonstrates circadian rhythms. Circadian control occurs through cryptoch...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349790/ https://www.ncbi.nlm.nih.gov/pubmed/28100634 http://dx.doi.org/10.1091/mbc.E16-08-0624 |