Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

Plasmodium falciparum causes malaria in humans with over 450,000 deaths annually. The asexual blood stage involves invasion of erythrocytes by merozoites, in which they grow and divide to release daughter merozoites, which in turn invade new erythrocytes perpetuating the cycle responsible for malari...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Lin, Xu, Yibin, Wong, Wilson, Thompson, Jennifer K, Healer, Julie, Goddard-Borger, Ethan D, Lawrence, Michael C, Cowman, Alan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349848/
https://www.ncbi.nlm.nih.gov/pubmed/28195530
http://dx.doi.org/10.7554/eLife.21347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349848/
https://www.ncbi.nlm.nih.gov/pubmed/28195530
http://dx.doi.org/10.7554/eLife.21347

Ejemplares similares