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An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites

Malaria parasites evade immune detection by growth and replication within erythrocytes. After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of nutrients from plasma. Here, we report that the parasite-encoded RhopH complex contributes to both invasion and channel-med...

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Detalles Bibliográficos
Autores principales: Ito, Daisuke, Schureck, Marc A, Desai, Sanjay A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349850/
https://www.ncbi.nlm.nih.gov/pubmed/28221136
http://dx.doi.org/10.7554/eLife.23485