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Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

Invasion of erythrocytes by Plasmodial merozoites is a composite process involving the interplay of several proteins. Among them, the Plasmodium falciparum Cysteine-Rich Protective Antigen (PfCyRPA) is a crucial component of a ternary complex, including Reticulocyte binding-like Homologous protein 5...

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Detalles Bibliográficos
Autores principales: Favuzza, Paola, Guffart, Elena, Tamborrini, Marco, Scherer, Bianca, Dreyer, Anita M, Rufer, Arne C, Erny, Johannes, Hoernschemeyer, Joerg, Thoma, Ralf, Schmid, Georg, Gsell, Bernard, Lamelas, Araceli, Benz, Joerg, Joseph, Catherine, Matile, Hugues, Pluschke, Gerd, Rudolph, Markus G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349852/
https://www.ncbi.nlm.nih.gov/pubmed/28195038
http://dx.doi.org/10.7554/eLife.20383