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Autophagy flux induced by ginsenoside-Rg3 attenuates human prion protein-mediated neurotoxicity and mitochondrial dysfunction

Mitochondrial quality control is a process by which mitochondria undergo successive rounds of fusion and fission with dynamic exchange of components to segregate functional and damaged elements. Removal of mitochondrion that contains damaged components is accomplished via autophagy. In this study, w...

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Detalles Bibliográficos
Autores principales: Moon, Ji-Hong, Lee, Ju-Hee, Lee, You-Jin, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349867/
https://www.ncbi.nlm.nih.gov/pubmed/27911875
http://dx.doi.org/10.18632/oncotarget.13730