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A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands

The effects of transforming growth factor beta (TGF-β) signaling on prostate tumorigenesis has been shown to be strongly dependent on the stage of development, with TGF-β functioning as a tumor suppressor in early stages of disease and as a promoter in later stages. To study in further detail the pa...

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Detalles Bibliográficos
Autores principales: Qin, Tai, Barron, Lindsey, Xia, Lu, Huang, Haojie, Villarreal, Maria M., Zwaagstra, John, Collins, Cathy, Yang, Junhua, Zwieb, Christian, Kodali, Ravindra, Hinck, Cynthia S., Kim, Sun Kyung, Reddick, Robert L., Shu, Chang, O’Connor-McCourt, Maureen D., Hinck, Andrew P., Sun, Lu-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349899/
https://www.ncbi.nlm.nih.gov/pubmed/27863384
http://dx.doi.org/10.18632/oncotarget.13343