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Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling

ADAR1, one of adenosine deaminases acting on RNA, modulates RNA transcripts through converting adenosine (A) to inosine (I) by deamination. Emerging evidence has implicated that ADAR1 plays an important role in a few of human cancers, however, its expression and physiological significance in gastric...

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Detalles Bibliográficos
Autores principales: Dou, Ning, Yu, Shijun, Ye, Xiaojuan, Yang, Dong, Li, Yandong, Gao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349904/
https://www.ncbi.nlm.nih.gov/pubmed/27863387
http://dx.doi.org/10.18632/oncotarget.13354