Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species

Ent-kaurane diterpene compounds have attracted considerable attention in recent years due to its antitumor, antibacterial, and antiviral activities. However, the clinical development of natural kaurane diterpenes, for example, oridonin for cancer therapy has been hampered by its relatively moderate...

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Detalles Bibliográficos
Autores principales: Ma, Yong-Cheng, Ke, Yu, Zi, Xiaolin, Zhao, Fei, Yuan, Lin, Zhu, Ying-Li, Fan, Xia-Xia, Zhao, Ning-Min, Li, Qiao-Yan, Qin, Yu-Hua, Liu, Hong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349908/
https://www.ncbi.nlm.nih.gov/pubmed/27863415
http://dx.doi.org/10.18632/oncotarget.13367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349908/
https://www.ncbi.nlm.nih.gov/pubmed/27863415
http://dx.doi.org/10.18632/oncotarget.13367

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