Myb expression is critical for myeloid leukemia development induced by Setbp1 activation

SETBP1 missense mutations have been frequently identified in multiple myeloid neoplasms; however, their oncogenic potential remains unclear. Here we show that expression of Setbp1 mutants carrying two such mutations in mouse bone marrow progenitors efficiently induced development of acute myeloid le...

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Detalles Bibliográficos
Autores principales: Nguyen, Nhu, Vishwakarma, Bandana A., Oakley, Kevin, Han, Yufen, Przychodzen, Bartlomiej, Maciejewski, Jaroslaw P., Du, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349915/
https://www.ncbi.nlm.nih.gov/pubmed/27863435
http://dx.doi.org/10.18632/oncotarget.13383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349915/
https://www.ncbi.nlm.nih.gov/pubmed/27863435
http://dx.doi.org/10.18632/oncotarget.13383

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