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Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia
In chronic lymphocytic leukemia (CLL), NOTCH1 gene mutations (NOTCH1(mut)) have been associated with adverse prognostic features but the independence of these as a prognostic factor is still controversial. In our study we validated a c.7541-7542delCT NOTCH1 mutation assay based on droplet digital PC...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349927/ https://www.ncbi.nlm.nih.gov/pubmed/27835908 http://dx.doi.org/10.18632/oncotarget.13246 |