Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia

In chronic lymphocytic leukemia (CLL), NOTCH1 gene mutations (NOTCH1(mut)) have been associated with adverse prognostic features but the independence of these as a prognostic factor is still controversial. In our study we validated a c.7541-7542delCT NOTCH1 mutation assay based on droplet digital PC...

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Detalles Bibliográficos
Autores principales: Minervini, Angela, Minervini, Francesco Crescenzio, Anelli, Luisa, Zagaria, Antonella, Casieri, Paola, Coccaro, Nicoletta, Cumbo, Cosimo, Tota, Giuseppina, Impera, Luciana, Orsini, Paola, Brunetti, Claudia, Giordano, Annamaria, Specchia, Giorgina, Albano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349927/
https://www.ncbi.nlm.nih.gov/pubmed/27835908
http://dx.doi.org/10.18632/oncotarget.13246

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