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Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients

We previously developed a novel tumor subtype classification model for duodenal adenocarcinomas based on a combination of the CpG island methylator phenotype (CIMP) and MLH1 methylation status. Here, we tested the prognostic value of this model in stage II colorectal cancer (CRC) patients. Tumors we...

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Detalles Bibliográficos
Autores principales: Fu, Tao, Liu, Yanliang, Li, Kai, Wan, Weiwei, Pappou, Emmanouil P., Iacobuzio-Donahue, Christine A., Kerner, Zachary, Baylin, Stephen B., Wolfgang, Christopher L., Ahuja, Nita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349928/
https://www.ncbi.nlm.nih.gov/pubmed/27880934
http://dx.doi.org/10.18632/oncotarget.13441