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Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients
We previously developed a novel tumor subtype classification model for duodenal adenocarcinomas based on a combination of the CpG island methylator phenotype (CIMP) and MLH1 methylation status. Here, we tested the prognostic value of this model in stage II colorectal cancer (CRC) patients. Tumors we...
Autores principales: | Fu, Tao, Liu, Yanliang, Li, Kai, Wan, Weiwei, Pappou, Emmanouil P., Iacobuzio-Donahue, Christine A., Kerner, Zachary, Baylin, Stephen B., Wolfgang, Christopher L., Ahuja, Nita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349928/ https://www.ncbi.nlm.nih.gov/pubmed/27880934 http://dx.doi.org/10.18632/oncotarget.13441 |
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