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Peroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer

Cancer stem cells (CSCs) are a key target for reducing tumor growth, metastasis, and recurrence. Redox status is a critical factor in the maintenance of CSCs, and the antioxidant enzyme Peroxiredoxin 2 (Prdx2) plays an important role in the development of colon cancer. Therefore, we investigated the...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Wei, Jinlai, Zhang, Shouru, Wu, Xingye, Guo, Jinbao, Liu, Maoxi, Du, Kunli, Xu, Jun, Peng, Linglong, Lv, Zhenbing, You, Wenxian, Xiong, Yongfu, Fu, Zhongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349956/
https://www.ncbi.nlm.nih.gov/pubmed/27894099
http://dx.doi.org/10.18632/oncotarget.13559