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Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation

The expression of intermediate filament Nestin is necessary for the neural progenitor cells (NPCs) to maintain stemness, but the underlying cellular and molecular mechanism remains unclear. In this study, we demonstrated that Nestin is required for the self-renew of NPCs through activating MAPK and...

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Detalles Bibliográficos
Autores principales: Hu, Wentao, Lu, Hong, Wang, Shang, Yin, Wenhan, Liu, Xujie, Dong, Lin, Chiu, Richard, Shen, Li, Lu, Wen-Jing, Lan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349970/
https://www.ncbi.nlm.nih.gov/pubmed/27894083
http://dx.doi.org/10.18632/oncotarget.13498