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Curcumin increases exosomal TCF21 thus suppressing exosome-induced lung cancer

Curcumin is a novel drug for lung cancer treatment. However, the mechanism underlying the anti-tumor effect of curcumin remains elusive. Previous evidences indicated that, the methylating transferase DNMT1 is downregulated by curcumin, and the transcription factor 21 (TCF21) is suppressed by DNMT1....

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Detalles Bibliográficos
Autores principales: Wu, Hao, Zhou, Jingcheng, Zeng, Chao, Wu, Da, Mu, Zhimin, Chen, Baokun, Xie, Yuancai, Ye, Yiwang, Liu, Jixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349972/
https://www.ncbi.nlm.nih.gov/pubmed/27894084
http://dx.doi.org/10.18632/oncotarget.13499