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Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice

Previous clinical reports have found elevated osteopontin (OPN) levels in tumor tissues to be indicative of greater malignancy in human hepatocellular carcinoma (HCC). However, the role of OPN on carcinogenesis and its underlying mechanism remain unclear. In the present study, we investigated the on...

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Detalles Bibliográficos
Autores principales: Lee, Su-Hyung, Park, Jun-Won, Woo, Sang-Ho, Go, Du-Min, Kwon, Hyo-Jung, Jang, Ja-June, Kim, Dae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349983/
https://www.ncbi.nlm.nih.gov/pubmed/27888617
http://dx.doi.org/10.18632/oncotarget.13529