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Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse

Anaplastic Lymphoma Kinase (ALK) is a transmembrane receptor kinase that belongs to the insulin receptor superfamily and has previously been shown to play a role in cell proliferation, migration and invasion in neuroblastoma. Activating ALK mutations are reported in both hereditary and sporadic neur...

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Detalles Bibliográficos
Autores principales: Chen, Lindi, Humphreys, Angharad, Turnbull, Lisa, Bellini, Angela, Schleiermacher, Gudrun, Salwen, Helen, Cohn, Susan L., Bown, Nick, Tweddle, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349989/
https://www.ncbi.nlm.nih.gov/pubmed/27888620
http://dx.doi.org/10.18632/oncotarget.13541