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Oral Immunization with Recombinant Lactobacillus acidophilus Expressing espA-Tir-M Confers Protection against Enterohemorrhagic Escherichia coli O157:H7 Challenge in Mice

Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157:H7) causes hemorrhagic colitis and the formation of characteristic attaching and effacing (A/E) lesions in humans. Given the severe sequelae of EHEC O157:H7 infection, it is critical to develop effective vaccines for human use. However, for achie...

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Detalles Bibliográficos
Autores principales: Lin, Ruqin, Zhang, Yiduo, Long, Beiguo, Li, Yawen, Wu, Yuhua, Duan, Siqin, Zhu, Bo, Wu, Xianbo, Fan, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350096/
https://www.ncbi.nlm.nih.gov/pubmed/28360900
http://dx.doi.org/10.3389/fmicb.2017.00417