Single Neuron Optimization as a Basis for Accurate Biophysical Modeling: The Case of Cerebellar Granule Cells

In realistic neuronal modeling, once the ionic channel complement has been defined, the maximum ionic conductance (G(i-max)) values need to be tuned in order to match the firing pattern revealed by electrophysiological recordings. Recently, selection/mutation genetic algorithms have been proposed to...

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Detalles Bibliográficos
Autores principales: Masoli, Stefano, Rizza, Martina F., Sgritta, Martina, Van Geit, Werner, Schürmann, Felix, D'Angelo, Egidio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350144/
https://www.ncbi.nlm.nih.gov/pubmed/28360841
http://dx.doi.org/10.3389/fncel.2017.00071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350144/
https://www.ncbi.nlm.nih.gov/pubmed/28360841
http://dx.doi.org/10.3389/fncel.2017.00071

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