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Single Neuron Optimization as a Basis for Accurate Biophysical Modeling: The Case of Cerebellar Granule Cells
In realistic neuronal modeling, once the ionic channel complement has been defined, the maximum ionic conductance (G(i-max)) values need to be tuned in order to match the firing pattern revealed by electrophysiological recordings. Recently, selection/mutation genetic algorithms have been proposed to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350144/ https://www.ncbi.nlm.nih.gov/pubmed/28360841 http://dx.doi.org/10.3389/fncel.2017.00071 |