Cthrc1 lowers pulmonary collagen associated with bleomycin‐induced fibrosis and protects lung function

Idiopathic pulmonary fibrosis (IPF) involves collagen deposition that results in a progressive decline in lung function. This process involves activation of Smad2/3 by transforming growth factor (TGF)‐β and Wnt signaling pathways. Collagen Triple Helix Repeat‐Containing‐1 (Cthrc1) protein inhibits S...

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Detalles Bibliográficos
Autores principales: Binks, Andrew P., Beyer, Megyn, Miller, Ryan, LeClair, Renee J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350163/
https://www.ncbi.nlm.nih.gov/pubmed/28292882
http://dx.doi.org/10.14814/phy2.13115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350163/
https://www.ncbi.nlm.nih.gov/pubmed/28292882
http://dx.doi.org/10.14814/phy2.13115

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