Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii

Saporin (SAP) or SAP conjugates injected into the nucleus tractus solitarii (NTS) of rats kill astrocytes. When injected in its unconjugated form, SAP produces no demonstrable loss of or damage to local neurons. However bilateral injections of SAP significantly attenuate responses to activation of b...

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Detalles Bibliográficos
Autores principales: Talman, William T., Dragon, Deidre Nitschke, Lin, Li‐Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350171/
https://www.ncbi.nlm.nih.gov/pubmed/28270593
http://dx.doi.org/10.14814/phy2.13158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350171/
https://www.ncbi.nlm.nih.gov/pubmed/28270593
http://dx.doi.org/10.14814/phy2.13158

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